A Machine Learning-Driven Approach to Quantifying Coronary Artery Tortuosity
JACC: Advances, 5(6 Pt 2):1028292026
Interpretable machine learning for clinical decision-making.
I am a fifth-year PhD candidate in Applied Mathematics at Harvard University, advised by Finale Doshi-Velez. I develop interpretable machine-learning methods for clinical decision-making, with applications in cardiovascular imaging and precision psychiatry. I am part of Harvard’s Data to Actionable Knowledge Lab and the Fahed Lab at the Broad Institute and Massachusetts General Hospital.
I develop methods to understand what predictive models learn and how their information compares with expert knowledge, including Signature Activation and Shared Canonical Component Removal.
I use machine learning to extract measurable features from coronary angiography and study their relationship with disease, including coronary artery tortuosity.
I study factors associated with antidepressant treatment dropout and investigate what predictive models can reveal beyond expert-defined clinical features.
JACC: Advances, 5(6 Pt 2):1028292026
arXiv:2309.114432023
arXiv:2610.138192026
JAMA Netw Open 8(1):e24553682025