Jose Roberto Tello Ayala

Jose Roberto Tello Ayala

Interpretable machine learning for clinical decision-making.

PhD Candidate in Applied Mathematics

Data to Actionable Knowledge Lab

Harvard John A. Paulson School of Engineering and Applied Sciences

I am a fifth-year PhD candidate in Applied Mathematics at Harvard University, advised by Finale Doshi-Velez. I develop interpretable machine-learning methods for clinical decision-making, with applications in cardiovascular imaging and precision psychiatry. I am part of Harvard’s Data to Actionable Knowledge Lab and the Fahed Lab at the Broad Institute and Massachusetts General Hospital.

Research Themes

Interpretability and model auditing

I develop methods to understand what predictive models learn and how their information compares with expert knowledge, including Signature Activation and Shared Canonical Component Removal.

Cardiovascular imaging

I use machine learning to extract measurable features from coronary angiography and study their relationship with disease, including coronary artery tortuosity.

Precision psychiatry

I study factors associated with antidepressant treatment dropout and investigate what predictive models can reveal beyond expert-defined clinical features.

Education

 
 
 
 
 
Harvard University
PhD Candidate in Applied Mathematics
Harvard University
August 2022 – Present Cambridge MA, USA
 
 
 
 
 
Instituto Tecnológico Autónomo de México
Bachelor of Science in Applied Mathematics
Instituto Tecnológico Autónomo de México
August 2015 – December 2019 Mexico City, Mexico
Graduated with honors by acquiring a special mention thanks to my thesis titled “A study concerning the Chebyshev Center problem in finite-dimensional normed vector spaces” under the supervision of Dr. Cesar Garcia-Garcia.